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An Egr-1-specific DNAzyme regulates Egr-1 and proliferating cell nuclear antigen expression in rat vascular smooth muscle cells

The aim of the present study was to transfect rat aortic smooth muscle cells with an early growth response factor-1 (Egr-1)-specific DNAzyme (ED5), to observe its effect on Egr-1 and proliferating cell nuclear antigen (PCNA) expression and to elucidate the mechanism of ED5-mediated inhibition of vas...

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Detalles Bibliográficos
Autores principales: ZHANG, JUNBIAO, GUO, CHANGLEI, WANG, RAN, HUANG, LULI, LIANG, WANQIAN, LIU, RUNNAN, SUN, BING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671740/
https://www.ncbi.nlm.nih.gov/pubmed/23737882
http://dx.doi.org/10.3892/etm.2013.1013