Conformational templating of α-synuclein aggregates in neuronal-glial cultures

BACKGROUND: Genetic studies have established a causative role for α-synuclein (αS) in Parkinson’s disease (PD), and the presence of αS aggregates in the form of Lewy body (LB) and Lewy neurite (LN) protein inclusions are defining pathological features of PD. Recent data has established that extracel...

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Detalles Bibliográficos
Autores principales: Sacino, Amanda N, Thomas, Michael A, Ceballos-Diaz, Carolina, Cruz, Pedro E, Rosario, Awilda M, Lewis, Jada, Giasson, Benoit I, Golde, Todd E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671973/
https://www.ncbi.nlm.nih.gov/pubmed/23714769
http://dx.doi.org/10.1186/1750-1326-8-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671973/
https://www.ncbi.nlm.nih.gov/pubmed/23714769
http://dx.doi.org/10.1186/1750-1326-8-17

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