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Conformational templating of α-synuclein aggregates in neuronal-glial cultures
BACKGROUND: Genetic studies have established a causative role for α-synuclein (αS) in Parkinson’s disease (PD), and the presence of αS aggregates in the form of Lewy body (LB) and Lewy neurite (LN) protein inclusions are defining pathological features of PD. Recent data has established that extracel...
Autores principales: | Sacino, Amanda N, Thomas, Michael A, Ceballos-Diaz, Carolina, Cruz, Pedro E, Rosario, Awilda M, Lewis, Jada, Giasson, Benoit I, Golde, Todd E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671973/ https://www.ncbi.nlm.nih.gov/pubmed/23714769 http://dx.doi.org/10.1186/1750-1326-8-17 |
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