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Blocking Mineralocorticoid Receptors Impairs, Blocking Glucocorticoid Receptors Enhances Memory Retrieval in Humans

Memory retrieval is impaired at very low as well as very high cortisol levels, but not at intermediate levels. This inverted-U-shaped relationship between cortisol levels and memory retrieval may originate from different roles of the mineralocorticoid (MR) and glucocorticoid receptor (GR) that bind...

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Detalles Bibliográficos
Autores principales: Rimmele, Ulrike, Besedovsky, Luciana, Lange, Tanja, Born, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671995/
https://www.ncbi.nlm.nih.gov/pubmed/23303058
http://dx.doi.org/10.1038/npp.2012.254