TWEAK-Independent Fn14 Self-Association and NF-κB Activation Is Mediated by the C-Terminal Region of the Fn14 Cytoplasmic Domain

The tumor necrosis factor (TNF) superfamily member TNF-like weak inducer of apoptosis (TWEAK) is a pro-inflammatory and pro-angiogenic cytokine implicated in physiological tissue regeneration and wound repair. TWEAK binds to a 102-amino acid type I transmembrane cell surface receptor named fibroblas...

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Detalles Bibliográficos
Autores principales: Brown, Sharron A. N., Cheng, Emily, Williams, Mark S., Winkles, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672086/
https://www.ncbi.nlm.nih.gov/pubmed/23750247
http://dx.doi.org/10.1371/journal.pone.0065248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672086/
https://www.ncbi.nlm.nih.gov/pubmed/23750247
http://dx.doi.org/10.1371/journal.pone.0065248

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