2-Aminopurine Enhances the Oncolytic Activity of an E1b-Deleted Adenovirus in Hepatocellular Carcinoma Cells

Adenoviruses with deletions of viral genes have been extensively studied as potential cancer therapeutics. Although a high degree of cancer selectivity has been demonstrated with these conditionally replicating adenoviruses, low levels of virus replication can be detected in normal cells. Furthermor...

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Detalles Bibliográficos
Autores principales: Sharon, David, Schümann, Michael, MacLeod, Sheena, McPherson, Robyn, Chaurasiya, Shyambabu, Shaw, Andrew, Hitt, Mary M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672087/
https://www.ncbi.nlm.nih.gov/pubmed/23750246
http://dx.doi.org/10.1371/journal.pone.0065222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672087/
https://www.ncbi.nlm.nih.gov/pubmed/23750246
http://dx.doi.org/10.1371/journal.pone.0065222

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