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Aptamer Selection Based on G4-Forming Promoter Region

We developed a method for aptamer identification without in vitro selection. We have previously obtained several aptamers, which may fold into the G-quadruplex (G4) structure, against target proteins; therefore, we hypothesized that the G4 structure would be an excellent scaffold for aptamers to rec...

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Detalles Bibliográficos
Autores principales: Yoshida, Wataru, Saito, Taiki, Yokoyama, Tomomi, Ferri, Stefano, Ikebukuro, Kazunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672139/
https://www.ncbi.nlm.nih.gov/pubmed/23750264
http://dx.doi.org/10.1371/journal.pone.0065497