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Elevated Protein Carbonylation, and Misfolding in Sciatic Nerve from db/db and Sod1(−/−) Mice: Plausible Link between Oxidative Stress and Demyelination

Diabetic peripheral polyneuropathy is associated with decrements in motor/sensory neuron myelination, nerve conduction and muscle function; however, the mechanisms of reduced myelination in diabetes are poorly understood. Chronic elevation of oxidative stress may be one of the potential determinants...

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Detalles Bibliográficos
Autores principales: Hamilton, Ryan T., Bhattacharya, Arunabh, Walsh, Michael E., Shi, Yun, Wei, Rochelle, Zhang, Yiqiang, Rodriguez, Karl A., Buffenstein, Rochelle, Chaudhuri, Asish R., Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672154/
https://www.ncbi.nlm.nih.gov/pubmed/23750273
http://dx.doi.org/10.1371/journal.pone.0065725