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Characterization of the Oligomerization and Aggregation of Human Serum Amyloid A

The fibrillation of Serum Amyloid A (SAA) – a major acute phase protein – is believed to play a role in the disease Amyloid A (AA) Amyloidosis. To better understand the amyloid formation pathway of SAA, we characterized the oligomerization, misfolding, and aggregation of a disease-associated isoform...

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Detalles Bibliográficos
Autores principales: Patke, Sanket, Srinivasan, Saipraveen, Maheshwari, Ronak, Srivastava, Sunit K., Aguilera, J. Javier, Colón, Wilfredo, Kane, Ravi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672174/
https://www.ncbi.nlm.nih.gov/pubmed/23750222
http://dx.doi.org/10.1371/journal.pone.0064974