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Induction of Autophagy by a Novel Small Molecule Improves Aβ Pathology and Ameliorates Cognitive Deficits

Growing evidence has demonstrated a neuroprotective role of autophagy in Alzheimer’s disease (AD). Thus, autophagy has been regarded as a potential therapeutic target, attracting increasing interest in pharmaceutical autophagy modulation by small molecules. We designed a two-cycle screening strategy...

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Detalles Bibliográficos
Autores principales: Chu, Cheng, Zhang, Xinjiang, Ma, Wei, Li, Li, Wang, Wei, Shang, Lu, Fu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672196/
https://www.ncbi.nlm.nih.gov/pubmed/23750258
http://dx.doi.org/10.1371/journal.pone.0065367