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Induction of Autophagy by a Novel Small Molecule Improves Aβ Pathology and Ameliorates Cognitive Deficits
Growing evidence has demonstrated a neuroprotective role of autophagy in Alzheimer’s disease (AD). Thus, autophagy has been regarded as a potential therapeutic target, attracting increasing interest in pharmaceutical autophagy modulation by small molecules. We designed a two-cycle screening strategy...
Autores principales: | Chu, Cheng, Zhang, Xinjiang, Ma, Wei, Li, Li, Wang, Wei, Shang, Lu, Fu, Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672196/ https://www.ncbi.nlm.nih.gov/pubmed/23750258 http://dx.doi.org/10.1371/journal.pone.0065367 |
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