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Protective Effects of Andrographolide Analogue AL-1 on ROS-Induced RIN-mβ Cell Death by Inducing ROS Generation
Oxidative stress is considered to be a major factor contributing to pathogenesis and progression of many diseases. A novel andrographolide-lipoic acid conjugate (AL-1) could protect pancreatic β-cells from reactive oxygen species (ROS)-induced oxidative injury. However, its protective mechanism is s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672203/ https://www.ncbi.nlm.nih.gov/pubmed/23750203 http://dx.doi.org/10.1371/journal.pone.0063656 |