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The archaeal DnaG protein needs Csl4 for binding to the exosome and enhances its interaction with adenine-rich RNAs

The archaeal RNA-degrading exosome contains a catalytically active hexameric core, an RNA-binding cap formed by Rrp4 and Csl4 and the protein annotated as DnaG (bacterial type primase) with so-far-unknown functions in RNA metabolism. We found that the archaeal DnaG binds to the Csl4-exosome but not...

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Detalles Bibliográficos
Autores principales: Hou, Linlin, Klug, Gabriele, Evguenieva-Hackenberg, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672285/
https://www.ncbi.nlm.nih.gov/pubmed/23324612
http://dx.doi.org/10.4161/rna.23450