Cargando…
The archaeal DnaG protein needs Csl4 for binding to the exosome and enhances its interaction with adenine-rich RNAs
The archaeal RNA-degrading exosome contains a catalytically active hexameric core, an RNA-binding cap formed by Rrp4 and Csl4 and the protein annotated as DnaG (bacterial type primase) with so-far-unknown functions in RNA metabolism. We found that the archaeal DnaG binds to the Csl4-exosome but not...
Autores principales: | Hou, Linlin, Klug, Gabriele, Evguenieva-Hackenberg, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672285/ https://www.ncbi.nlm.nih.gov/pubmed/23324612 http://dx.doi.org/10.4161/rna.23450 |
Ejemplares similares
-
Archaeal DnaG contains a conserved N-terminal RNA-binding domain and enables tailing of rRNA by the exosome
por: Hou, Linlin, et al.
Publicado: (2014) -
iCLIP analysis of RNA substrates of the archaeal exosome
por: Bathke, Jochen, et al.
Publicado: (2020) -
The SmAP1/2 proteins of the crenarchaeon Sulfolobus solfataricus interact with the exosome and stimulate A-rich tailing of transcripts
por: Märtens, Birgit, et al.
Publicado: (2017) -
Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria
por: Zhou, Yingqin, et al.
Publicado: (2017) -
Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction
por: Chilingaryan, Zorik, et al.
Publicado: (2018)