Cargando…

Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response

INTRODUCTION: Glycyrrhizin (GL) was recently found to suppress high-mobility group box 1 (HMGB1)-induced injury by binding directly to it. However, the effect of GL on HMGB1 expression in endotoxemia as well as its underlying molecular mechanism remained unclear. METHODS: Twenty-one pigs were divide...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Wei, Zhao, Feng, Fang, Yong, Li, Xiantao, Shen, Lei, Cao, Tongwa, Zhu, Hechen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672474/
https://www.ncbi.nlm.nih.gov/pubmed/23497622
http://dx.doi.org/10.1186/cc12558