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Glycyrrhizin protects against porcine endotoxemia through modulation of systemic inflammatory response
INTRODUCTION: Glycyrrhizin (GL) was recently found to suppress high-mobility group box 1 (HMGB1)-induced injury by binding directly to it. However, the effect of GL on HMGB1 expression in endotoxemia as well as its underlying molecular mechanism remained unclear. METHODS: Twenty-one pigs were divide...
Autores principales: | Wang, Wei, Zhao, Feng, Fang, Yong, Li, Xiantao, Shen, Lei, Cao, Tongwa, Zhu, Hechen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672474/ https://www.ncbi.nlm.nih.gov/pubmed/23497622 http://dx.doi.org/10.1186/cc12558 |
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