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A useful EGFR-TK ligand for tumor diagnosis with SPECT: development of radioiodinated 6-(3-morpholinopropoxy)-7-ethoxy-4-(3′-iodophenoxy)quinazoline

OBJECTIVE: Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, radioiodinated 4-(3-iodophenoxy)-6,7-diethoxyquinazoline (PHY) was reported to possess good characteristics as a tumor imaging agent. We have explored the fea...

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Detalles Bibliográficos
Autores principales: Hirata, Masahiko, Kanai, Yasukazu, Naka, Sadahiro, Yoshimoto, Mitsuyoshi, Kagawa, Shinya, Matsumuro, Keiji, Katsuma, Hideyuki, Yamaguchi, Hiroshi, Magata, Yasuhiro, Ohmomo, Yoshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672506/
https://www.ncbi.nlm.nih.gov/pubmed/23494210
http://dx.doi.org/10.1007/s12149-013-0703-y