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Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial)

INTRODUCTION: Several observational studies suggest that statins modulate the pathophysiology of sepsis and may prevent its progression. The aim of this study was to determine if the acute administration of atorvastatin reduces sepsis progression in statin naïve patients hospitalized with sepsis. ME...

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Detalles Bibliográficos
Autores principales: Patel, Jaimin M, Snaith, Catherine, Thickett, David R, Linhartova, Lucie, Melody, Teresa, Hawkey, Peter, Barnett, Anthony H, Jones, Alan, Hong, Tan, Cooke, Matthew W, Perkins, Gavin D, Gao, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672620/
https://www.ncbi.nlm.nih.gov/pubmed/23232151
http://dx.doi.org/10.1186/cc11895