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Evaluation of the novel folate receptor ligand [(18)F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis

INTRODUCTION: Detection of (subclinical) synovitis is relevant for both early diagnosis and monitoring of therapy of rheumatoid arthritis (RA). Previously, the potential of imaging (sub)clinical arthritis was demonstrated by targeting the translocator protein in activated macrophages using (R)-[(11)...

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Detalles Bibliográficos
Autores principales: Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Smith, Desirée EC, Kularatne, Sumith A, Jansen, Gerrit, Low, Philip S, Lammertsma, Adriaan A, van der Laken, Conny J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672671/
https://www.ncbi.nlm.nih.gov/pubmed/23452511
http://dx.doi.org/10.1186/ar4191