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CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice

INTRODUCTION: The ability to ameliorate murine lupus renders regulatory T cells (Treg) a promising tool for the treatment of systemic lupus erythematosus (SLE). In consideration to the clinical translation of a Treg-based immunotherapy of SLE, we explored the potential of CD4+Foxp3+ Treg to maintain...

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Detalles Bibliográficos
Autores principales: Weigert, Olivia, von Spee, Caroline, Undeutsch, Reinmar, Kloke, Lutz, Humrich, Jens Y, Riemekasten, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672693/
https://www.ncbi.nlm.nih.gov/pubmed/23446139
http://dx.doi.org/10.1186/ar4188