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BMP/Coco antagonism as a deterministic factor of metastasis dormancy in lung

A recent Cell publication demonstrates that the secreted antagonist of transforming growth factor-beta ligands, Coco, can re-activate previously dormant metastatic breast cancer cells specifically in the lung by inhibiting bone morphogenetic protein (BMP) signaling. The authors provided evidence for...

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Detalles Bibliográficos
Autores principales: Martinez, Jarrod, Zhang, Xiang H-F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672727/
https://www.ncbi.nlm.nih.gov/pubmed/23320613
http://dx.doi.org/10.1186/bcr3350