CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts

INTRODUCTION: Osteoarthritis (OA) is the most common degenerative joint disease that is involved in the degradation of articular cartilage. The exact etiology of OA is not completely understood. CCN4 is related to up-regulation in the cartilage of patients with osteoarthritis. Previous studies have...

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Detalles Bibliográficos
Autores principales: Hou, Chun-Han, Tang, Chih-Hsin, Hsu, Chin-Jung, Hou, Sheng-Mon, Liu, Ju-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672729/
https://www.ncbi.nlm.nih.gov/pubmed/23343403
http://dx.doi.org/10.1186/ar4151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672729/
https://www.ncbi.nlm.nih.gov/pubmed/23343403
http://dx.doi.org/10.1186/ar4151

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