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Anti-matrix metalloproteinase-9 DNAzyme decreases tumor growth in the MMTV-PyMT mouse model of breast cancer

INTRODUCTION: Despite continued improvements in diagnosis, surgical techniques, and chemotherapy, breast cancer patients are still overcome by cancer metastasis. Tumor cell proliferation, invasion and metastasis are mediated, at least in part, through degradation of basement membrane by neutral matr...

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Detalles Bibliográficos
Autores principales: Hallett, Miranda A, Teng, Bin, Hasegawa, Hisashi, Schwab, Luciana P, Seagroves, Tiffany N, Pourmotabbed, Tayebeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672740/
https://www.ncbi.nlm.nih.gov/pubmed/23407024
http://dx.doi.org/10.1186/bcr3385