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Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium

INTRODUCTION: The molecular circuitry of different cell types dictates their normal function as well as their response to oncogene activation. For instance, mice lacking the Wip1 phosphatase (also known as PPM1D; protein phosphatase magnesium-dependent 1D) have a delay in HER2/neu (human epidermal g...

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Detalles Bibliográficos
Autores principales: Tarulli, Gerard A, De Silva, Duvini, Ho, Victor, Kunasegaran, Kamini, Ghosh, Kakaly, Tan, Bryan C, Bulavin, Dmitry V, Pietersen, Alexandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672744/
https://www.ncbi.nlm.nih.gov/pubmed/23369183
http://dx.doi.org/10.1186/bcr3381