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The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus

INTRODUCTION: An NZB-derived genetic locus (Sle2c2) that suppresses autoantibody production in a mouse model of induced systemic lupus erythematosus contains a polymorphism in the gene encoding the G-CSF receptor. This study was designed to test the hypothesis that the Sle2c2 suppression is associat...

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Detalles Bibliográficos
Autores principales: Lantow, Margareta, Sivakumar, Ramya, Zeumer, Leilani, Wasserfall, Clive, Zheng, Ying-Yi, Atkinson, Mark A, Morel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672747/
https://www.ncbi.nlm.nih.gov/pubmed/23566364
http://dx.doi.org/10.1186/ar4208