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Endoplasmic reticulum stress induces PRNP prion protein gene expression in breast cancer

INTRODUCTION: High prion protein (PrP) levels are associated with breast, colon and gastric cancer resistance to treatment and with a poor prognosis for the patients. However, little is known about the underlying molecular mechanism(s) regulating human PrP gene (PRNP) expression in cancers. Because...

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Detalles Bibliográficos
Autores principales: Déry, Marc-André, Jodoin, Julie, Ursini-Siegel, Josie, Aleynikova, Olga, Ferrario, Cristiano, Hassan, Saima, Basik, Mark, LeBlanc, Andréa C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672785/
https://www.ncbi.nlm.nih.gov/pubmed/23497519
http://dx.doi.org/10.1186/bcr3398