A rheumatoid factor paradox: inhibition of rituximab effector function

INTRODUCTION: Rituximab (RTX) therapy of rheumatoid arthritis (RA) exhibits enhanced effectiveness in seropositive patients. Using patient sera, we tested if this improved efficacy was associated with enhanced RTX mediated complement-dependent cytotoxicity (RTX-CDC). METHODS: We developed an in vitr...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Jonathan D, Shyu, Irene, Newkirk, Marianna M, Rigby, William FC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672827/
https://www.ncbi.nlm.nih.gov/pubmed/23351360
http://dx.doi.org/10.1186/ar4152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672827/
https://www.ncbi.nlm.nih.gov/pubmed/23351360
http://dx.doi.org/10.1186/ar4152

Ejemplares similares