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A rheumatoid factor paradox: inhibition of rituximab effector function

INTRODUCTION: Rituximab (RTX) therapy of rheumatoid arthritis (RA) exhibits enhanced effectiveness in seropositive patients. Using patient sera, we tested if this improved efficacy was associated with enhanced RTX mediated complement-dependent cytotoxicity (RTX-CDC). METHODS: We developed an in vitr...

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Detalles Bibliográficos
Autores principales:	Jones, Jonathan D, Shyu, Irene, Newkirk, Marianna M, Rigby, William FC
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672827/ https://www.ncbi.nlm.nih.gov/pubmed/23351360 http://dx.doi.org/10.1186/ar4152

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