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c-Myc modulates microRNA processing via the transcriptional regulation of Drosha

The c-Myc oncogenic transcription factor is known to regulate microRNA (miRNA) expression at the transcriptional level. However, little is known about the function of c-Myc in miRNA processing. Here, we report that Drosha, one of the most important components of the miRNA processing machinery, is a...

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Detalles Bibliográficos
Autores principales: Wang, Xingwu, Zhao, Xiaocheng, Gao, Ping, Wu, Mian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672885/
https://www.ncbi.nlm.nih.gov/pubmed/23735886
http://dx.doi.org/10.1038/srep01942