A C. elegans Screening Platform for the Rapid Assessment of Chemical Disruption of Germline Function

Background: Despite the developmental impact of chromosome segregation errors, we lack the tools to assess environmental effects on the integrity of the germline in animals. Objectives: We developed an assay in Caenorhabditis elegans that fluorescently marks aneuploid embryos after chemical exposure...

Descripción completa

Detalles Bibliográficos
Autores principales: Allard, Patrick, Kleinstreuer, Nicole C., Knudsen, Thomas B., Colaiácovo, Monica P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672921/
https://www.ncbi.nlm.nih.gov/pubmed/23603051
http://dx.doi.org/10.1289/ehp.1206301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672921/
https://www.ncbi.nlm.nih.gov/pubmed/23603051
http://dx.doi.org/10.1289/ehp.1206301

Ejemplares similares