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A C. elegans Screening Platform for the Rapid Assessment of Chemical Disruption of Germline Function
Background: Despite the developmental impact of chromosome segregation errors, we lack the tools to assess environmental effects on the integrity of the germline in animals. Objectives: We developed an assay in Caenorhabditis elegans that fluorescently marks aneuploid embryos after chemical exposure...
Autores principales: | Allard, Patrick, Kleinstreuer, Nicole C., Knudsen, Thomas B., Colaiácovo, Monica P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672921/ https://www.ncbi.nlm.nih.gov/pubmed/23603051 http://dx.doi.org/10.1289/ehp.1206301 |
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