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Signal integration in TGF-β, WNT, and Hippo pathways

Complete sequences of animal genomes have revealed a remarkably small and conserved toolbox of signalling pathways, such as TGF-β and WNT that account for all biological diversity. This raises the question as to how such a limited set of cues elaborates so many diverse cell fates and behaviours. It...

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Detalles Bibliográficos
Autores principales: Attisano, Liliana, Wrana, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672943/
https://www.ncbi.nlm.nih.gov/pubmed/23755364
http://dx.doi.org/10.12703/P5-17