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Biochemical and biophysical characterization of four EphB kinase domains reveals contrasting thermodynamic, kinetic and inhibition profiles
The Eph (erythropoietin-producing hepatocellular carcinoma) B receptors are important in a variety of cellular processes through their roles in cell-to-cell contact and signalling; their up-regulation and down-regulation has been shown to have implications in a variety of cancers. A greater understa...
Autores principales: | Overman, Ross C., Debreczeni, Judit E., Truman, Caroline M., McAlister, Mark S., Attwood, Teresa K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673036/ https://www.ncbi.nlm.nih.gov/pubmed/23627399 http://dx.doi.org/10.1042/BSR20130028 |
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