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Modelling HIV-1 2-LTR dynamics following raltegravir intensification

A model of reservoir activation and viral replication is introduced accounting for the production of 2-LTR HIV-1 DNA circles following antiviral intensification with the HIV integrase inhibitor raltegravir, considering contributions of de novo infection events and exogenous sources of infected cells...

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Detalles Bibliográficos
Autores principales: Luo, Rutao, Cardozo, E. Fabian, Piovoso, Michael J., Wu, Hulin, Buzon, Maria J., Martinez-Picado, Javier, Zurakowski, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673152/
https://www.ncbi.nlm.nih.gov/pubmed/23658114
http://dx.doi.org/10.1098/rsif.2013.0186