A powerful and efficient set test for genetic markers that handles confounders

Motivation: Approaches for testing sets of variants, such as a set of rare or common variants within a gene or pathway, for association with complex traits are important. In particular, set tests allow for aggregation of weak signal within a set, can capture interplay among variants and reduce the b...

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Detalles Bibliográficos
Autores principales: Listgarten, Jennifer, Lippert, Christoph, Kang, Eun Yong, Xiang, Jing, Kadie, Carl M., Heckerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673214/
https://www.ncbi.nlm.nih.gov/pubmed/23599503
http://dx.doi.org/10.1093/bioinformatics/btt177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673214/
https://www.ncbi.nlm.nih.gov/pubmed/23599503
http://dx.doi.org/10.1093/bioinformatics/btt177

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