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Predicting the functional consequences of cancer-associated amino acid substitutions
Motivation: The number of missense mutations being identified in cancer genomes has greatly increased as a consequence of technological advances and the reduced cost of whole-genome/whole-exome sequencing methods. However, a high proportion of the amino acid substitutions detected in cancer genomes...
Autores principales: | Shihab, Hashem A., Gough, Julian, Cooper, David N., Day, Ian N. M., Gaunt, Tom R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673218/ https://www.ncbi.nlm.nih.gov/pubmed/23620363 http://dx.doi.org/10.1093/bioinformatics/btt182 |
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