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Passive and active DNA methylation and the interplay with genetic variation in gene regulation

DNA methylation is an essential epigenetic mark whose role in gene regulation and its dependency on genomic sequence and environment are not fully understood. In this study we provide novel insights into the mechanistic relationships between genetic variation, DNA methylation and transcriptome seque...

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Detalles Bibliográficos
Autores principales: Gutierrez-Arcelus, Maria, Lappalainen, Tuuli, Montgomery, Stephen B, Buil, Alfonso, Ongen, Halit, Yurovsky, Alisa, Bryois, Julien, Giger, Thomas, Romano, Luciana, Planchon, Alexandra, Falconnet, Emilie, Bielser, Deborah, Gagnebin, Maryline, Padioleau, Ismael, Borel, Christelle, Letourneau, Audrey, Makrythanasis, Periklis, Guipponi, Michel, Gehrig, Corinne, Antonarakis, Stylianos E, Dermitzakis, Emmanouil T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673336/
https://www.ncbi.nlm.nih.gov/pubmed/23755361
http://dx.doi.org/10.7554/eLife.00523