Monoubiquitination of EEA1 regulates endosome fusion and trafficking

BACKGROUND: Early endosomal autoantigen 1 (EEA1) is a membrane tethering factor required for the fusion and maturation of early endosomes in endocytosis. How the activity of EEA1 is regulated in cells is unclear. RESULTS: Here we show that endogenous EEA1 is prone to monoubiquitination at multiple s...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramanathan, Harish N, Zhang, Guofeng, Ye, Yihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673817/
https://www.ncbi.nlm.nih.gov/pubmed/23701900
http://dx.doi.org/10.1186/2045-3701-3-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673817/
https://www.ncbi.nlm.nih.gov/pubmed/23701900
http://dx.doi.org/10.1186/2045-3701-3-24

Ejemplares similares