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Monoubiquitination of EEA1 regulates endosome fusion and trafficking
BACKGROUND: Early endosomal autoantigen 1 (EEA1) is a membrane tethering factor required for the fusion and maturation of early endosomes in endocytosis. How the activity of EEA1 is regulated in cells is unclear. RESULTS: Here we show that endogenous EEA1 is prone to monoubiquitination at multiple s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673817/ https://www.ncbi.nlm.nih.gov/pubmed/23701900 http://dx.doi.org/10.1186/2045-3701-3-24 |