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Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents

BACKGROUND: Alzheimer’s disease (AD), a progressive and degenerative disorder, has become one of the severe problems among the aged population all over the world. To use cholinesterase inhibitor drugs has become the most predominant treatment strategy for AD. RESULTS: A series of novel 1, 3-dihydrox...

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Detalles Bibliográficos
Autores principales: Qin, Jiangke, Lan, Wenli, Liu, Zhong, Huang, Jun, Tang, Huang, Wang, Hengshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673835/
https://www.ncbi.nlm.nih.gov/pubmed/23622085
http://dx.doi.org/10.1186/1752-153X-7-78