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The highly pathogenic H7N3 avian influenza strain from July 2012 in Mexico acquired an extended cleavage site through recombination with host 28S rRNA

BACKGROUND: A characteristic difference between highly and non-highly pathogenic avian influenza strains is the presence of an extended, often multibasic, cleavage motif insertion in the hemagglutinin protein. Such motif is found in H7N3 strains from chicken farm outbreaks in 2012 in Mexico. METHODS...

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Detalles Bibliográficos
Autores principales: Maurer-Stroh, Sebastian, Lee, Raphael TC, Gunalan, Vithiagaran, Eisenhaber, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673898/
https://www.ncbi.nlm.nih.gov/pubmed/23635025
http://dx.doi.org/10.1186/1743-422X-10-139