X-ray irradiation promotes apoptosis of hippocampal neurons through up-regulation of Cdk5 and p25

BACKGROUND: Cranial radiation therapy has been used for the treatment of primary and metastatic brain tumors. A prominent feature of brain injury induced by the radiation therapy is hippocampal dysfunction, characterized by a decline in memory. Cdk5 plays an important role in memory formation. Abnor...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Ai-Min, Li, Chuan-Gang, Han, Yong-Qing, Liu, Que-Ling, Xia, Qiong, Yuan, Ya-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673899/
https://www.ncbi.nlm.nih.gov/pubmed/23688022
http://dx.doi.org/10.1186/1475-2867-13-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673899/
https://www.ncbi.nlm.nih.gov/pubmed/23688022
http://dx.doi.org/10.1186/1475-2867-13-47

Ejemplares similares