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Suppression of Gluconeogenic Gene Expression by LSD1-Mediated Histone Demethylation
Aberrant gluconeogenic gene expression is associated with diabetes, glycogen storage disease, and liver cancer. However, little is known how these genes are regulated at the chromatin level. In this study, we investigated in HepG2 cells whether histone demethylation is a potential mechanism. We foun...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673910/ https://www.ncbi.nlm.nih.gov/pubmed/23755305 http://dx.doi.org/10.1371/journal.pone.0066294 |