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Frailty in Old Age Is Associated with Decreased Interleukin-12/23 Production in Response to Toll-Like Receptor Ligation

Aging is associated with progressive alterations of immune functions, leading to higher susceptibility to bacterial and viral infections and reduced vaccine responses. Data concerning cytokine production in response to Toll-like receptor (TLR) ligands are highly variable in old people, reflecting th...

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Detalles Bibliográficos
Autores principales: Compté, Nathalie, Zouaoui Boudjeltia, Karim, Vanhaeverbeek, Michel, De Breucker, Sandra, Tassignon, Joel, Trelcat, Anne, Pepersack, Thierry, Goriely, Stanislas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673922/
https://www.ncbi.nlm.nih.gov/pubmed/23755218
http://dx.doi.org/10.1371/journal.pone.0065325