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Complex Multi-Block Analysis Identifies New Immunologic and Genetic Disease Progression Patterns Associated with the Residual β-Cell Function 1 Year after Diagnosis of Type 1 Diabetes

The purpose of the present study is to explore the progression of type 1 diabetes (T1D) in Danish children 12 months after diagnosis using Latent Factor Modelling. We include three data blocks of dynamic paraclinical biomarkers, baseline clinical characteristics and genetic profiles of diabetes rela...

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Detalles Bibliográficos
Autores principales: Andersen, Marie Louise Max, Rasmussen, Morten Arendt, Pörksen, Sven, Svensson, Jannet, Vikre-Jørgensen, Jennifer, Thomsen, Jane, Hertel, Niels Thomas, Johannesen, Jesper, Pociot, Flemming, Petersen, Jacob Sten, Hansen, Lars, Mortensen, Henrik Bindesbøl, Nielsen, Lotte Brøndum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674006/
https://www.ncbi.nlm.nih.gov/pubmed/23755131
http://dx.doi.org/10.1371/journal.pone.0064632