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Complex Multi-Block Analysis Identifies New Immunologic and Genetic Disease Progression Patterns Associated with the Residual β-Cell Function 1 Year after Diagnosis of Type 1 Diabetes
The purpose of the present study is to explore the progression of type 1 diabetes (T1D) in Danish children 12 months after diagnosis using Latent Factor Modelling. We include three data blocks of dynamic paraclinical biomarkers, baseline clinical characteristics and genetic profiles of diabetes rela...
Autores principales: | Andersen, Marie Louise Max, Rasmussen, Morten Arendt, Pörksen, Sven, Svensson, Jannet, Vikre-Jørgensen, Jennifer, Thomsen, Jane, Hertel, Niels Thomas, Johannesen, Jesper, Pociot, Flemming, Petersen, Jacob Sten, Hansen, Lars, Mortensen, Henrik Bindesbøl, Nielsen, Lotte Brøndum |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674006/ https://www.ncbi.nlm.nih.gov/pubmed/23755131 http://dx.doi.org/10.1371/journal.pone.0064632 |
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