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Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer

Here, we interrogated head and neck cancer (HNSCC) specimens (n = 12) to examine if different metabolic compartments (oxidative vs. glycolytic) co-exist in human tumors. A large panel of well-established biomarkers was employed to determine the metabolic state of proliferative cancer cells. Interest...

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Detalles Bibliográficos
Autores principales: Curry, Joseph M., Tuluc, Madalina, Whitaker-Menezes, Diana, Ames, Julie A., Anantharaman, Archana, Butera, Aileen, Leiby, Benjamin, Cognetti, David M., Sotgia, Federica, Lisanti, Michael P., Martinez-Outschoorn, Ubaldo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674065/
https://www.ncbi.nlm.nih.gov/pubmed/23574725
http://dx.doi.org/10.4161/cc.24092