Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops

Establishment of cell polarity—or symmetry breaking—relies on local accumulation of polarity regulators. Although simple positive feedback is sufficient to drive symmetry breaking, it is highly sensitive to stochastic fluctuations typical for living cells. Here, by integrating mathematical modelling...

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Detalles Bibliográficos
Autores principales: Freisinger, Tina, Klünder, Ben, Johnson, Jared, Müller, Nikola, Pichler, Garwin, Beck, Gisela, Costanzo, Michael, Boone, Charles, Cerione, Richard A., Frey, Erwin, Wedlich-Söldner, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674238/
https://www.ncbi.nlm.nih.gov/pubmed/23651995
http://dx.doi.org/10.1038/ncomms2795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674238/
https://www.ncbi.nlm.nih.gov/pubmed/23651995
http://dx.doi.org/10.1038/ncomms2795

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