SUMO2/3 modification of cyclin E contributes to the control of replication origin firing

The small ubiquitin-like modifier (SUMO) pathway is essential for the maintenance of genome stability. We investigated its possible involvement in the control of DNA replication during S phase by using the Xenopus cell-free system. Here we show that the SUMO pathway is critical to limit the number a...

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Detalles Bibliográficos
Autores principales: Bonne-Andrea, Catherine, Kahli, Malik, Mechali, Francisca, Lemaitre, Jean-Marc, Bossis, Guillaume, Coux, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674260/
https://www.ncbi.nlm.nih.gov/pubmed/23673635
http://dx.doi.org/10.1038/ncomms2875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674260/
https://www.ncbi.nlm.nih.gov/pubmed/23673635
http://dx.doi.org/10.1038/ncomms2875

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