ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα

Gliomas are resistant to radiation therapy, as well as to TNFα induced killing. Radiation-induced TNFα triggers Nuclear factor κB (NFκB)-mediated radioresistance. As inhibition of NFκB activation sensitizes glioma cells to TNFα-induced apoptosis, we investigated whether TNFα modulates the responsive...

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Detalles Bibliográficos
Autores principales: Sinha, S, Ghildiyal, R, Mehta, V S, Sen, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674344/
https://www.ncbi.nlm.nih.gov/pubmed/23640457
http://dx.doi.org/10.1038/cddis.2013.128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674344/
https://www.ncbi.nlm.nih.gov/pubmed/23640457
http://dx.doi.org/10.1038/cddis.2013.128

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